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NJM Packaging: Aseptic filling, stoppering and capping machine for vials

NJM Packaging has introduced the quick-changeover Dara SX-310-PP/D aseptic filling, stoppering and capping machine for vials.

Aseptic filling, stoppering and capping machine for vials
Aseptic filling, stoppering and capping machine for vials

Dara can equip this system with stainless steel or ceramic rotary piston pumps or peristaltic pumps that utilize single use tubing. Featuring fully servo-driven automation and a compact footprint, the SX-310-PP/D offers accurate filling and precise stoppering and capping. It is low maintenance, achieves fast and easy changeover, and has simple set-up for adding new container sizes in the future.

Ideal for the pharmaceutical, biotech and cosmetic manufacturer filling suspensions, vaccines, or cellular tissue, the unit aseptically fills glass or plastic vials with dosing volumes from 0.1 to 250 ml for liquids and from 2 to 1,500 mg for powders. The system can be programmed for full stopper insertion, followed by aluminum/flip-off cap application, or half stopper insertion and no capping for lyophilization. It can be changed over to handle a new product in 15 min. with no tools required.

Featuring two filling, two stoppering and two capping stations, the linear, intermittent-motion system handles throughputs of up to 120 units/min. within a compact footprint only 106 in. (270 cm) long and 30 in. (76 cm) wide. The rotary piston pumps achieve +/- 0.5 percent accuracy and the peristaltic pumps offer +/- 1 percent accuracy. The closing station features a servo-driven tangential rolling head to minimize particulate generation.

For sterile or clean room applications, the SX-310-PP/D can be equipped with a laminar air flow (LAF), open or closed restricted access barrier system (oRABS/cRABS) or a high containment isolator system. Optional clean-in-place (CIP), sterilization-in-place (SIP) or gas flushing are also available.

Ancillary equipment from Dara, such as automatic or manual denesting units, adapts this machine for ready-to-fill vials. Trays can be manually fed to the SX-310-PP/D or the system can be integrated with an upstream washer and depyrogenation tunnel for continuous automated feeding. An integrated rotary table single files vials for presentation to the filling heads. Bags of stoppers are loaded into a vibratory hopper/circular feeder that delivers stoppers to a pick-and-place station that inserts the stoppers. Filled and closed vials are directed to output trays for manual unloading or they can be integrated with downstream equipment.


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