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Pharmaceutical Liquid Filling Monobloc with Dual-Weight Verification

BellatRx’s Constellation Monobloc is a new servo-driven fill-weigh-cap system for unstable pharmaceutical microtubes, vials, and cartridges.

Constellation 1

The size and shape of certain vials and microtubes can make them difficult to stand on their own, adding difficulty in automated filling because they cannot be placed on a standard conveyor and moved from one machine to another.

Life sciences manufacturers producing high value liquid drugs may also be challenged by inaccurate fill volume or weight control, or product loss at the end of a batch.

To combat these issues, BellatRx Inc. has launched its Constellation Monobloc to pre-weigh, fill, post-weigh, cap, torque, and inspect vials to insure adherence to specifications. The system is suited to small and large batches of high-value liquid products where accuracy is key for pharma, biotech, diagnostic, and healthcare customers. Constellation is able to index unstable vials in a safe way that prevents tilting or leaking. It features a standard speed of 60 vials/min, with higher speeds available with dual-robotic stations.

What really sets the system apart is its dual-weight control of vials and microtubes before filling and after filling. β€œThe system measures a tare weight and gross weight, subtracting the tare to obtain an accurate net weight as a verification of the fill volume,” says Alan Shuhaibar, president at BellatRx. This eliminates the risk of underfilled vials.

Operation

Robotic pick and place stations unload vials from trays into pucks that index the tubes gently throughout the process of filling, capping, and inspection. Grippers match the diameter of the vials for delicate handling. At the filling station, servo-controlled pumps deliver precise volumes into vials, and nozzles are lifted to reduce contact and reduce aeration.

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