Part 1: From Drug Supply to Staffing, the Benefits of RFID Integrated into Vial Labels

In this Q&A, a manager of pharmacy operations explains why RFID-embedded vial labels just may change the world of inventory management and dispensing.

With the CCL/Kit Check partnership, manufacturers receive labels with RFID inlay that appear identical to their existing label—and don’t require artwork changes and new FDA approval—and do not affect packaging lines.
With the CCL/Kit Check partnership, manufacturers receive labels with RFID inlay that appear identical to their existing label—and don’t require artwork changes and new FDA approval—and do not affect packaging lines.

Automated inventory management solutions are used for a variety of different products, including medications and equipment. Their popularity continues to grow in tracking drugs for efficiency benefits across health systems.

We talked with Eric Schaefer, PharmD, manager of pharmacy operations at Allegheny Health Network, about how using label systems from Kit Check and CCL Healthcare has opened doors, increased efficiency, and more.

Before we get into the benefits—and Schaefer explains there are many—we’ll go over the technology that makes this possible. Kit Check and CCL Healthcare have partnered to deliver labels embedded with RFID tags to pharmaceutical manufacturers.

RFID inlay for small vials

Until recently, flag labels with RFID tags were manually applied to individual vials at the hospital system. The labels could not be applied at the manufacturer due to the time-consuming nature of the process. “Additionally, pharmaceutical companies use specific adhesives which are tested against migration and anything that can affect the drug,” says Karl Hoelper, director of marketing at CCL.

CCL has integrated the RFID inlay into the existing vial label that they print for the manufacturer. Vials then arrive at the hospital pre-tagged, eliminating the flag-application workflow at the hospital.

“Because we're producing the label already, we can take a transfer tape and match that adhesive so there are no qualification issues for the pharmaceutical company, which is a pretty big hurdle—it could be a year or two years to qualify,” explains Hoelper. “This mitigates the risks of any chemical migrating off the label and into the drug.”

Glass, liquid, and small vial/syringe sizes—including the traditional 2 mL vial—all pose challenges for RFID functionality. In addition to these challenges, the RFID inlay needs to be rotated 90 degrees in order for the antenna to fit properly on the 2 mL vial.

To make integrated RFID labels a reality on small vials, CCL custom-built a machine to orient inlays so that manufacturers wouldn’t have to change any aspects of their label artwork. The machinery allows them to remove each RFID inlay from the reel, pick it up, rotate it, and space it properly.

To make integrated RFID labels a reality on small vials, CCL custom-built a machine to orient inlays so that manufacturers wouldn’t have to change any aspects of their label artwork.To make integrated RFID labels a reality on small vials, CCL custom-built a machine to orient inlays so that manufacturers wouldn’t have to change any aspects of their label artwork.

The process requires extreme precision with multiple sensors and camera systems on the line to ensure the tag fits behind the label. The labels undergo numerous quality checks before they are released.

The result is that manufacturers receive labels with RFID inlay that appear identical to their existing label—and don’t require artwork changes and new FDA approval—and do not affect packaging lines. “We're working within the constraint of the current label, which is key for that 2 mL vial,” says Hoelper. “We wanted to make sure we made this work with their current adhesive and current label so that adding RFID is as painless as possible.” 

DoseID 

With the goal of ensuring the quality, performance, and interoperability of RFID tagged drug products as they move through the supply chain, DoseID launched in August 2020. CCL and Kit Check are founding members of this self-governing consortium established to unify the industry around an approach to serialized, RFID-tagged pharmaceutical products. “Creating pharma specific RFID labels is irrelevant unless there is an interoperable supply chain that sees the value of RFID. DoseID substantiates that value,” says the consortium.

They report that they take serialization beyond DSCSA, from the unit of sale to the unit of use. DoseID uniquely serializes every dose, container, or device to track every action taken upon it during its entire lifecycle.

The consortium takes a practical approach to ensure that the system works in the rigors of the real world. DoseID drugs and hardware devices are compliant with existing standards like RAIN and GS1. They are tested to ensure (1) performance (the best inlay is chosen for the application), (2) interoperability so that the drug will read in real-world scenarios, and (3) complete and accurate data in which the evolving record of a drug's attributes and event history is stored in the cloud and accessible to all parties.

Pharmaceutical Innovations Report
Discover the latest breakthrough packaging technologies shaping the pharmaceutical sector. This report dives into cutting-edge innovations, from smart containers that enhance patient safety to eco-friendly materials poised to transform the industry’s sustainability practices. All from PACK EXPO. Learn how forward-thinking strategies are driving efficiency and redefining what’s possible in pharma packaging.
Learn More
Pharmaceutical Innovations Report
Coding, Marking, and Labeling Innovations Report
Explore our editor-curated report featuring cutting-edge coding, labeling, and RFID innovations from PACK EXPO 2024. Discover high-speed digital printing, sustainable label materials, automated labeling systems, and advanced traceability solutions that are transforming packaging operations across industries.
Access Report
Coding, Marking, and Labeling Innovations Report