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Dissimilar packs share honors

A powder medication inhaler and unusual bags for an ice melter and for pet food earn recognition at DuPont's 12th awards competition.

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Unlike their food counterparts (see story, p. 76), the three DuPont award-winning products discussed here have little in common. What they do share is package innovation. Schering-Plough's dry powder inhaler (1), winner of a gold award, is a perfectly good example.

Kenilworth, NJ-based Schering-Plough continues to conduct clinical trials for a steroid-based dry powder inhaler. The inhaler has a novel patented design with a counting mechanism which allows the patient to know the number of doses remaining at all times.

Reproducible dosing has been demonstrated with the delivery system that operates over a broad range of inspiratory flow rates. In use, the dose is positioned in an inhalation channel when the cap is removed by what Schering calls cap-activation. Upon inspiration, the drug in the form of free-flowing agglomerates impinges on a specially designed internal nozzle that reproducibly reduces the agglomerates to a fine particle fraction of drug.

Imtiaz Chaudry, Ph.D., vice president, pharmaceutical development, Schering-Plough Research Institute, managed a team that developed the packaging/drug delivery system.

Thomas Ambrosio, Ph.D., development fellow at the Institute, reports, "The container uses a combination of plastics. The polypropylene exterior provides a moisture barrier. The bulk of the interior, including the reservoir, dose plate, support plates and counter rings are acrylonitrile butadiene styrene. The ABS allows for precision molding. Polyester is used for a pawl in the counter mechanism." Schering-Plough Corp. holds the patents for the systems and designs.

Although Packaging World had details about the product, commercialization and names of suppliers involved in the design and assembly of container parts, Schering-Plough asked us not to publish them.

"The person simply breathes in the product and the inhaler precisely meters the proper dose," says Ambrosio. He says the metering system not only emits reproducible doses, but its design makes accidental double dosing virtually impossible. In addition, the patient will always know the number of doses remaining because the inhaler has a numerical counter. The inhaler earned a gold award in the non-food category from DuPont (Wilmington, DE).

Shake and seal bag

Another gold award winner in DuPont's non-food category was the ShakerPAK(TM)(2), a practical and innovative bag used by Sylacauga, AL-based Pursell Industries for its Alaskan(TM) Ice Melt (see PW, March '98, p. 42). Between late '97 and early '98, the company shipped 75ꯠ of these handled, resealable zippered bags that are supplied pre-made by Kapak (Minneapolis, MN).

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