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MIT’s Needle-Free Injection Device Comes to Market

MIT spinoff Portal Instruments developed a jet-injection device that delivers drugs via a high-pressure stream with little to no pain.

Needle-Free Injection / Image: Portal Instruments
Needle-Free Injection / Image: Portal Instruments

No one likes getting a shot, but a recent article from MIT News discussed a new device that could exonerate some of the anxiety associated with it. An MIT spinout called Portal Instruments developed a jet-injection device that delivers drugs via a high-pressure stream that’s as thin as a strand of hair. It penetrates the skin with little to no pain, to administer adjustable dosages of drugs.

Last month, Portal announced a collaboration with Japanese pharma company Takeda to further develop the device and commercialize it under the name PRIME. The first candidate for the delivery device is ENTYVIO, an antibody for adults with Crohn’s disease. As part of the deal, portal will receive an initial payment with the potential for milestone earnings of up to $100 million.

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INTRODUCING! The Latest Trends for All Industries at PACK EXPO Southeast
The exciting new PACK EXPO Southeast 2025 unites all vertical markets in one dynamic hub, generating more innovative answers to your production challenges. Don’t miss this extraordinary opportunity for your business!
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INTRODUCING! The Latest Trends for All Industries at PACK EXPO Southeast