Concerns have been raised about how synthetic chemicals may affect different bodily systems of humans and animals causing numerous health problems. For example a new book that focuses on substances that affect the endocrine system warns consumers to avoid food in plastic containers and instructs them not to heat or microwave food in plastic containers or plastic wrap. D'Amato slipped an eleventh-hour amendment requiring the program into the Safe Drinking Water Act passed by the Senate. Opponents are hoping it can be modified in either the House bill or the House-Senate conference. EPA has indicated that an all-encompassing screening program is unrealistic and that only those substances raising real concerns should be targeted.