Download Download this free, 150-page Pharmaceutical Serialization Playbook jam-packed with strategies for success and pitfalls to avoid.  Learn more >>
Article |

High-assurance capping, sealing & bottle counting

In addition to flexible changeover, Glaxo Wellcome's clinical trial packaging line makes a high priority of quality-assured packaging. Its capper, sealer and bottle packer/counter are designed to maximize accuracy while minimizing errors.
FILED IN:  Controls  > Strategy

The hopper-fed Euro-Cap rotary capper from Kalish provides real-time torque inspection. A strain-gauge cell built into the capper measures the torque of each cap; if it's outside preset limits the bottle is rejected. Previously torque inspection was limited to manual tests of randomly sampled containers. Following cap inspection is an Enercon (Menomonee Falls WI) induction sealer. It has a unique speed control from Kalish that enables Glaxo Wellcome to validate that every bottle has passed through the sealer at the proper conveyor speed and hence is properly sealed. The control consists of a PLC tied to an encoder on the conveyor. If the conveyor is running too slowly for a proper seal the PLC delivers more current to the conveyor to speed it up. If the conveyor is moving too quickly the speed control slows it down. If for whatever reason the conveyor is physically unable to run at the speed that's specificed by the PLC an alarm sounds. After bottles pass through a retorquer they proceed into a unique custom built machine from AGR that counts bottles and drops them loose into polyethylene-lined cases. It's not so much a case packer as it is a highly accurate bottle counter that uses multiple light curtains to register and confirm the passage of each bottle. Air bursts are used to blow bottles off the conveyor and into the waiting box. The counter was necessary since Glaxo Wellcome needed a way to count out the exact number of bottles dictated by a given trial. "It's been a lifesaver" says Dean Kazan supervisor clinical supplies primary packaging. "We used to have a collection table at the end where we'd offload these by hand."

Related Sponsored Content

44 Best Package Designs
Sign up to receive timely updates from our editors and download this e-book of our editors’ selections for most innovative package designs of the past year.


Don't miss intelligence crucial to your job and business!
Click on any newsletter to view a sample. Enter your email address below to sign up!
Each newsletter ranges in frequency from once per month to a few times per month at most.